During the body’s natural detoxification processes, potentially detrimental molecules such as hormone metabolites, alcohol, drugs and air pollutants are removed from the blood stream via the liver. Healthy hormone detoxification is a crucial part of the normal functioning of the immune system. Diindolylmethane (DIM) is one molecule known for the supportive role it plays in stimulating natural detoxification enzymes and supporting normal hormone metabolism.
As a natural component derived from indole-3-carbinole and cruciferous vegetables, DIM has shown in studies to support the 2-hydroxylation instead of 16-hydroxylation of certain estrogen metabolites. This favors the production of 2-hydroxysterone over the more deleterious 16-hydroxyestrone. Other studies indicate that diindolylmethane may play important roles in inducing apoptosis and supporting the body’s normal angiogenic balance, especially in regards to healthy breast, cervical and prostate cells. †
Microencapsulated DIM® is the only diindolymethane with proven absorption and activity demonstrated in independently performed clinical studies. BioResponse DIM® contains pure DIM, microencapsulated in particles complexed with a vitamin E derivative and phospholipids to aid absorption from our intestinal tract. The patented formulation process for making BioResponse DIM® creates microparticles of DIM, emulsifies the DIM with vitamin E and phospholipids, and captures these complexes through a drying process in larger particles of pure food starch. The result is a sustained-release, dry powder which re-dissolves easily after oral consumption.
Serving Size: 1 Vegetarian Capsule
Servings Per Container: 60
MERIVA® Curcumin Phytosome …..125 mg
(Curcuma longa extract, rhizome/Phosphatidylcholine (soy) complex)
Green tea extract (leaf) …..200 mg
(standardized to 95% polyphenols and 45% EGCG)
BioResponse DIM® complex …..125 mg
(complex of starch, diindolylmethane, d-alpha tocopheryl succinate, phosphatidylcholine [soy] and silica), (standardized to contain 25% diindolylmethane)
Wasabia japonica (rhizome) …..50 mg
(containing at least 1,200 mcg of isothiocyantes as allyl ITC, 3-butenyl ITC, and 4-pentyl ITC)
Other Ingredients: Hydroxypropyl methylcellulose (capsule)‚ dicalcium phosphate‚ silica‚ vegetable stearate and cellulose.
Adults take one capsule‚ one to two times daily or as directed by your healthcare professional.