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B-12 500 mcg 100t by Douglas Labs

B-12 500 mcg by Douglas Laboratories supplies 500 mcg of Vitamin B-12 in each easy to swallow tablet. Vitamin B-12 may be a useful dietary supplement for individuals who wish to increase their intake of Vitamin B-12. Vitamin B-12 is essential for normal energy metabolism of carbohydrates, fat and protein. As a cofactor for methylmalonyl-CoA mutase enzymes, vitamin B-12 helps convert odd chain fatty acids and branched chain amino acids into succinyl-CoA, a common citric acid cycle intermediate.

Vitamin B-12 is also required for nucleic acid (DNA) synthesis, methionine synthesis from cysteine, and normal myelin synthesis in the nervous system. Along with Vitamin B-6 and folic acid, adequate levels of Vitamin B-12 are required to maintain normal plasma homocysteine levels. Elevated plasma homocysteine may be an independent risk factor for developing cardiovascular disease.

There are two distinct mechanisms for intestinal Vitamin B-12 absorption; receptor-mediated absorption and passive diffusion. In the first, vitamin B-12 attaches to a salivary “R-binder” protein which transports it into the small intestine, where vitamin B-12 is released. The vitamin then binds to “Intrinsic Factor” (IF), a glycoprotein normally produced by the gastric parietal cells. This vitamin B-12-IF complex is carried down to the ileum, where it binds to mucosal receptors. Finally, the complex is absorbed and bound to serum vitamin B-12-binding proteins. The second absorption mechanism, passive diffusion, does not require any carriers, such as B-binder or IF. Only about 1% of free vitamin B-12 is passively absorbed, but this can be nutritionally significant with higher dietary vitamin B-12 intakes.

Almost 40% of the population is suggested to have “low normal” plasma B-12 levels. Strict vegetarians, the elderly, and HIV/AIDS patients are often at risk for vitamin B-12 deficiency, either due to low dietary intake or impaired absorption. In the elderly, hypo- or achlorhydria maintains the binding of the vitamin with dietary proteins, leading to malabsorption. Vitamin B-12 deficiency can lead to CNS impairment, including cognition.

SKU: DL0450 Product Categories: , Health Condition:

$9.90

Description

Vitamin B-12 Tablet
A Dietary Supplement
100 Tablets

Ingredients:
Serving Size: 1 tablet
Servings Per Container: 100

Amount Per Serving
Vitamin B-12 …500 mcg
(Cyanocobalamin)

Contains:
Cellulose, Vegetable Stearate, Silica

Does Not Contain:
Yeast, Wheat, Gluten, Soy Protein, Milk/Dairy, Corn, Sodium, Sugar, Starch, Artificial Coloring, Preservatives, Flavoring

Dosage:
As a dietary supplement, adults take 1 tablet 1 to 2 times daily or as directed by your healthcare professional.

WARNINGS:
KEEP OUT OF REACH OF CHILDREN.

For optimal storage conditions, store in a cool, dry place.
(59º-77ºF/15º-25ºC)
(35-65% relative humidity)

Tamper resistant package, do not use if outer seal is missing.

 

Brand

Douglas Labs

At Douglas Laboratories, there is no greater mission than assuring that each and every supplement produced is of the highest quality. When you see the Douglas Laboratories Quality Emblem, be assured that only the finest raw materials are being used, and that all manufacturing is performed under the strictest of guidelines. Because these products are developed specifically for exclusive distribution by healthcare professionals, our emblem has become a recognized symbol of quality that patients around the world have come to rely upon and trust.
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