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In what has become one of my favorite articles (“Reversal of cognitive decline: a novel therapeutic program”), Dr. Dale Bredesen out of the UCLA Department of Neurology reports on a promising new approach to preserving brain function and even reversing cognitive impairment in humans. The program is comprehensive, personalized, and consistent with our own approach to preventing early memory loss. It includes most of the lifestyle behaviors we regularly preach as well as many of our go to supplements and nutraceuticals.
| Core Cognitive Cocktail | ||||
| Supplement | Key Ingredients | Directions | Rationale | |
| FolaNAC | L-methylfolate, methylcobalamine, NAC | 1 cap per day | Lower inflammation, Reduce oxidative stress, Help build key neurotransmitters | |
| RememorAll | P5P, Resveratrol, Bacopa, ginkgo, Huperzine, ALCAR, vinpocetine, phosphatidylserine | As directed on bottle | Enhance cognition, Increase SirT1 activity, Increase acetycholine | |
| Nrf2 Pathway Activator | Turmeric, Broccoli Seed Extract, Black Pepper Extract, Pterostilbenes | As directed on bottle | Reduce A-beta accumulation, Optimize mitochondrial health, Lower inflammation, Heal and seal the gut | |
| Super EPA Fishoil | 720 mg EPA
480 mg DHA (per serving) |
2 gel caps twice daily with meals | Lower inflammation, Heal and seal gut, Preserve synaptic structural integrity | |
| Tri Flora Probiotic | Multi strain with s. boulardii | 1 cap twice daily with meals | Right size inflammation, Heal and seal gut | |
| D3 5000 | Vitamin D3 | 1 cap per day | Powerful neurohormone that reduces inflammation | |
Bredesen DE. Aging (Albany NY). 2014 Sep;6(9):707-17.
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