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Spectracell MTHFR Genotyping

$172.00
SKU: SPECMG2
MTHFR is an enzyme responsible for converting 5,10-methylenetetrahydrofolate to the product 5-methyltetrahydrofolate - it is involved in the metabolism of folate and homocysteine. The product of the reaction catalyzed by MTHFR converts homocysteine (a potentially toxic amino acid) to methionine (a useful and necessary amino acid).
Blood draw required (Click here for draw sites)
 

Purchase on our secure website.
Lab order is provided by us.
You receive a collection kit for saliva, urine, or finger stick to collect at home and mail to the lab. Some tests require a blood draw at a local lab.
You receive the results by email within 2-3 weeks.
Got insurance? Some tests are covered. Call 800 385-7863 for more information.
Practitioner phone consultations available, some included with test.

 
Why is MTHFR Genotyping Important?

Certain mutations in the gene coding for MTHFR produce an enzyme that has reduced activity.
Reduced activity can lead to elevated levels of homocysteine (a.k.a. hyperhomocysteinemia), especially when folate levels are low.
High homocysteine (>13umol/L) may double the risk of developing illness or complications.
MTHFR genotyping can provide information about potential causes of elevated homocysteine and approaches for addressing it.
Based on MTHFR and homocysteine results, physicians can develop dietary and medical recommendations - increased intake of folate alone or in combination with vitamins B6 and B12 are recommended.
Based on results, recommendations for methotrexate dosage can be adjusted.

Risks Associated with MTHFR Variants/High Homocysteine:

Cardiovascular Disease
Cerebral Vascular Disease (Stroke)
Venous and Arterial Thrombosis
Methotrexate Toxicity for Cancer Therapy

Who Should be Tested?

Those with high homocysteine levels.
Those who have a familial history of cardiovascular disease, stroke or thrombosis.
Those who are candidates for long-term methotrexate therapy.
   
 

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