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Office Address:
Integrative Psychiatry
3392 Magic Oak Lane
Sarasota FL 34232

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Toll Free:(800) 385-7863
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The Link Between Brain Inflammation and Mental Health

Extensive research has shown that brain inflammation is connected to virtually all types of mental illness. Mood disorders such as depression and anxiety, as well as more serious conditions like autism, dementia, and even schizophrenia, have all been linked to inflammation of the brain.

Inflammation is also a contributing factor in such health issues as cardiovascular disease, asthma, and allergies; autoimmune diseases like arthritis and hypothyroidism may be influenced by inflammation as well.

What do we mean by inflammation, and why does it affect us negatively in so many ways?

Inflammation is an immune system response to environmental irritants, toxins, and infection. When the immune system is activated by one of these intruders, pro-inflammatory hormones signal the white blood cells to rush in and clean up the infected or damaged tissue. Once the invaders have been subdued, anti-inflammatory agents move in to begin the healing process.

In a normal immune system, a natural balance exists between inflammation and the anti-inflammatory agents. But in some cases, the immune system gets stuck in high gear, and symptoms of inflammation do not recede. This is known as chronic inflammation.

Inappropriate inflammation over a long period of time can lead to the damage or destruction of tissue; this tissue damage can ultimately lead to cardiovascular disease; cancer; neurodegenerative diseases such as Alzheimer's and Parkinson's disease and other forms of dementia; ADHD; autism; and mood disorders like anxiety and depression.

If you have had or are currently experiencing more than a few of the following health issues, this may be a sign that you have chronic inflammation:

- Seasonal/Environmental Allergies;
- Frequent colds, infections, sinusitis;
- Asthma or bronchitis;
- A history of frequent cold sores or canker sores;
- Acne, eczema, or skin rashes;
- Hepatitis;
- Exposure to environmental toxins (pesticides, heavy metals, industrial chemicals);
- A work environment with poor lighting or ventilation;
- Food allergies, sensitivities;
- Inflammatory bowel disease or colitis;
- Spastic colon;
- Osteoarthritis;
- An autoimmune disorder (rheumatoid arthritis, hypothyroid disease, lupus);
- Cardiovascular disease, including a history of heart attack;
- Type II diabetes or obesity;
- Alzheimer's or Parkinson's disease, or a family history of either;
- ADD/ADHD
- Autism
- Mood or behavioral disorders (depression, anxiety disorders, etc.);
- Consumption of more than 3 alcoholic beverages per week;
- Sedentary lifestyle, or less than 30 minutes of exercise 3X weekly.

If you are experiencing more than seven of these warning signs, you should be tested for inflammation.

Causes of Inflammation

What causes body and brain inflammation?

Digestive Imbalances

There is a great deal of evidence which suggests that inflammation has its roots in the gastrointestinal (GI) tract. The digestive system is designed to remove toxins, bacteria and viruses from our food before it has a chance to reach the rest of the body; the GI tract is the body's first line of defense against infection and disease.

Unfortunately, the digestive tract is often overwhelmed by what we put into it. Poor nutrition, medications, stress, and environmental toxins can damage the gut and cause inflammation, which is then free to spread unchecked throughout the rest of the body.

Regular consumption of foods such as the following are largely responsible for inflammation:

- Refined sugars;
- Processed and refined flours (white bread, cookies, pasta, crackers, and more);
- Foods high in acids;
- Dairy products;
- Animal fats;
- Caffeine;
- Alcohol;
- Food Allergens (hidden food allergies cause body and brain inflammation)

Environmental and lifestyle factors also affect inflammation:

- Exposure to toxic metals;(mercury, lead, cadmium)
- History of infections;
- Environmental toxins (pesticides, herbicides, food additives and preservatives)
- Chronic stress;
- Lack of exercise, sedentary habits;
- Nutritional deficiencies; ( B12, vitamin D, essential fatty acids, vitamin C)
- Overuse of antibiotics and acid blocking medications;
- Poor sleep habits.

Lab Tests for Inflammation

  • The C-reactive protein test is the most decisive test for detecting inflammation. This simple blood test can reveal high levels of C-reactive protein; CRP is produced by the liver in response to inflammation, infection and injury. It is available by fingerstick or blood draw.
  •  Food allergy testing can uncover immune responses which may point to inflammation.
  •  An inflammatory cytokine test can reveal evidence of inflammation, as well. Cytokines are proteins which act as messengers between immune cells to trigger an inflammatory response.

Inflammation Reduction Strategies

The good news is that there are several things you can do to promote your body's natural anti-inflammatory response and restore natural balance to your immune system.

* Exercise stimulates your body's anti-inflammatory abilities and keeps your blood circulating at its optimum level. Start off slowly, and work your way up until you are getting 20 to 30 minutes of exercise at a minimum of 3 times per week.

* Rest and stress management are vital to keeping your immune system in proper working order. Make sure you get enough sleep, and find a relaxation technique that you enjoy. Deep-breathing exercises are also an excellent restorative approach, do them 5 times a day, everyday.

Eat An Anti-Inflammatory Diet

* Make sure you get plenty of Omega-3 fatty acids. These oils are in short supply in our diet, and most people require a supplement to ensure they are getting enough Omega-3's in their system.

  • Avoid eating saturated fat by eating less butter, cream, cheese and other full-fat dairy products;
  • Avoid regular safflower and sunflower oils, corn oil, cottonseed oil, and mixed vegetable oils.
  • Avoid margarine, vegetable shortening, and all products listing them as ingredients. Avoid  products made with partially hydrogenated oils.
  • Eat  avocados and nuts, especially walnuts, cashews, almonds, and nut butters made from these nuts.
  • Good sources of omega-3 fatty acids are  salmon (preferably fresh or frozen wild or canned sockeye), sardines packed in water or olive oil, herring, omega-3 fortified eggs; hemp seeds and flaxseeds (preferably freshly ground); or take a fish oil supplement.

* A high-alkaline diet - one that includes plenty of green, leafy vegetables - is invaluable in combating
inflammation. Eat cruciferous (cabbage-family) vegetables regularly. Eat plenty of organic brightly colored fruits. Drink pomegranate juice, and green tea daily for their anti-oxidant effects.

*Eat more vegetable protein from soy products such as tofu, edamame, soynuts, and soymilk.

*Whole grains, brown rice, and bulgur wheat are less inflammatory than white flour products.

* Stay away from refined foods. Added sugars, convenience foods, and refined carbohydrates provide little nutritional value and provoke inflammation. In other words do not eat anything that comes from a bag or a box.

Anti-inflammatory supplements

Bioflavonoids and other beneficial anti-inflammatory herbs are gentle on your system and extremely useful in reducing inflammation.

  • Digestive Enzymes
  • Turmeric
  • Omega 3 Fatty Acids (fish oil)
  • Anti-inflammatory powder drinks
  • Herbal anti-inflammatory supplements

By making a few changes to your diet and lifestyle, you can find yourself feeling energized, refreshed, and filled with a sense of well-being. By taking steps to reduce inflammation, you will greatly improve the quality of your life.

Products:

AllerFood Food Allergy Test 96 Food Panel AllerFood Food Allergy Test 96 Food Panel -
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Aller-Food IgG Food Allergy Test by US BioTek test for 96 foods by finger stick. This quick and sensitive test identifies for food-specific IgG antibodies from a patient's blood spot sample. Simply, a lancet is used on the finger to obtain a few drops of blood, which are then absorbed onto our proprietary Micro-collection strips. These strips are then air-dried and sent in the mail to US BioTek for complete analysis. As with all of our ELISA assays, each and every patient's specimen is run in complete duplicate as part of our QA. Each patient report comes complete with a customized 4-Day Elimination/Rotation Diet Guideline. You receive the results. No doctors order needed!

SKU Price:Quantity:
biotek aller $235.00

Anti-InflammaLox comparable to Saloxicin Anti-InflammaLox comparable to Saloxicin -
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Anti-InflammaLox contains ingredients backed by years of use in traditional herbal medicine, as well as by published research in peer-reviewed journals. Boswellia serrata, white willow bark and bioflavonoids have all been shown to possess good anti-inflammatory and analgesic properties through the inhibition of COX-2 and 5-LOX enzymes. The proprietary bioflavonoid blend provides antioxidant protection against damage to soft tissue. * Anti-inflammatory * Analgesic * Antioxidant Support

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ofc xymo $24.90

Inflammatory Cytokine Blood Test Inflammatory Cytokine Blood Test -
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Inflammatory Cytokine Test can determine the presence of inflammatory Cytokines which can contribute to symptoms of depression, ADHD, Autism, schizophrenia, and numerous physical problems. Cytokines are powerful communication molecules capable of regulating a wide spectrum of biological functions, including a crucial role in the immuno-pathogenesis of disease. Neuroinflammation can lead neurons to self-destruct, with potentially disastrous consequences if it goes too far. Blood draw required for an additional fee (usually around $20.00) Doctors order provided, you receive a copy of the results.

SKU Price:Quantity:
5075 $340.00

Super EPA Molecularly Distilled 120 Capsules Super EPA Molecularly Distilled 120 Capsules -
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The Omega-3 Fatty Acids (FAs) abundant in fish oils are known for their many health benefits associated with their ability to support a healthy, balanced inflammatory response. Numerous scientific studies have demonstrated that Omega-3 FAs are important for the modulation of prostaglandin and leukotriene synthesis. These two classes of signaling molecules are critical for the maintenance of cardiovascular health, immune system function, and joint comfort. In addition, Omega-3 FAs are essential for the health of neuronal tissues, including the brain, and have been shown to play a role in both mood and cognition. Emerging evidence also indicates that Omega-3 FAs may be important in the maintenance of healthy body composition through a number of mechanisms. Stringent quality control standards in the production of Super EPA ensure this highly purified fish oil concentrate is free from toxic environmental contaminants and heavy metals like mercury.

SKU Price:Quantity:
ofcsuper $19.90

Advanced Inflammation Control 120 vcap Advanced Inflammation Control 120 vcap -
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Advanced Inflammation Control combines a comprehensive collection of ingredients designed to combat inflammation triggered by a host of lifestyle factors, including obesity/overweight, too little exercise, stress, sleep deprivation and excessive intake of sugar, starch, trans fatty acids, and vegetable oils.* The formula includes Stephania tetrandra and luteolin, both shown to suppress inflammatory mediators, and HolyBasil, a natural COX-2 inhibitor.* Other anti-inflammatory ingredients found in the formula are Boswellia serrata, green tea, ginger and nettle leaf.

SKU Price:Quantity:
P1625 em $49.95

Bio-Inflammatory 120 caps by BioGenesis Bio-Inflammatory 120 caps by BioGenesis -
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Bio-Inflammatory is designed to reduce inflammatory compounds with specialty nutrients and antioxidants (free radical quenchers). After neutralizing these inflammatory compounds, BioInflammatory™ assists the liver in removing them from the body. It does this by assisting the liver's Phase 1 and Phase 2 detoxification pathways.

SKU Price:Quantity:
BIO068 $36.00

C Reactive Protien Blood Test C Reactive Protien Blood Test -
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C Reactive Protien is a measurement of CRP by a high sensitivity assay, hs-CRP, allows for a lower detection limit related to chronic, low grade inflammation which is associated with heart disease. High Sensitivity C Reactive Protein may add to the predicative value of other markers used to assess a patient's risk of heart and peripheral vascular disease. You collect at the closest Lab. Doctors order provided. You receive a copy of the results.

SKU Price:Quantity:
lc 120766 $58.00

DNA Oxidative Damage Assay by Doctors Data DNA Oxidative Damage Assay by Doctors Data -
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DNA Oxidative Damage Assay by Doctors Data determines the level of oxidative stress which is involved in many pathophysiological processes, aging and cancer. Reactive oxygen species (ROS) are produced as a result of normal oxygen metabolism or exposure to xenobiotics. Excessive levels are associated with oxidative damage to lipids, proteins and DNA. Urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) is an excellent biomarker of oxidative stress and a risk factor for a variety of diseases including cancer. ROS-induced damage to nuclear and mitochondrial DNA occurs readily at the guanosine bases that are removed by DNA repair mechanisms and excreted in urine. Simple urine collection from home, Doctors order provided, you receive the results.

SKU Price:Quantity:
DD DNA $150.00

Dynamic Greens with Mangosteen Berry Flavor by Nutri-Dyn Dynamic Greens with Mangosteen Berry Flavor by Nutri-Dyn -
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Dynamic Greens with Mangosteen Berry Flavor by Nutri-Dyn is an easy-to-mix, as well as great tasting “phytonutrient” powder drink that is loaded with certified organic whole foods and concentrated plant extracts. Provides a “super-blend” of 100% natural mangosteen extract, vitamins, flax lignans, ionic trace minerals, enzymes, antioxidants, phytonutrients, and symbiotic intestinal flora. This dynamic blend supplies your body with boosted energy, metabolism, fat-burning, digestion, detoxification, immunity, repair, recovery, revitalization and longevity.

SKU Price:Quantity:
ND0886 $38.99

GI Effects Stool Analysis Profile GI Effects Stool Analysis Profile -
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GI Effects is the latest advancement in stool analysis for truly comprehensive results. GI Effects is unlike any other stool analysis profile, going beyond the standard parameters for identifying gastrointestinal disorders. GI Effects use DNA analysis to identify microbiota with 100% accuracy including anaerobes, a previously immeasurable area of the gut environment. Includes markers for inflammation, absorption, immunology, parasitology, and digeston.

SKU Price:Quantity:
metagi $395.00

InflamaSYN (Formerly Zyflamend) NewMark 60 softgels InflamaSYN (Formerly Zyflamend) NewMark 60 softgels -
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NewMark's patented InflamaSYN™ formulation represents a scientific breakthrough in promoting a healthy inflammation response.* Ongoing research from Columbia University, the Cleveland Clinic and the M.D. Anderson Cancer Center suggests that InflamaSYN provides broad-spectrum modulation of the enzymes and cell signals involved in eicosanoid metabolism.* Recent research studies suggest this may be an effective strategy to safely promote healthy function of the joints and musculoskeletal systems, the heart, brain, and immune system.* Extensive research into the herbal pharmacopoeia and international scientific literature databases has revealed that the following time-tested herbs, properly extracted and blended in the correct proportions, deliver dozens of phytonutrients that may safely and significantly promote a healthy inflammation response.*

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nm0043 $36.95

InflaMed by Allergy Research InflaMed by Allergy Research -
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Inflamed helps support the reduction of proinflammatory mediators, e.g. prostaglandins, thromboxanes. Helps support pain reduction associated with inflammation. Helps maintain detoxification systems, reducing inflammatory response. Helps reduce oxidative stress damage induced by inflammation.

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NP/EM $34.50

Inflammatone Designs For Health Inflammatone Designs For Health -
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Inflammatone is a powerful formula that combines the best enzyme technology for degrading fibrinolytic protein compounds produced during inflammation. The carefully chosen herbs have lipooxygenase (LOX) inhibition, COX 2 inhibition, only mild COX 1 inhibition (to avoid blood thinning and stomach sensitivity), as well as free radical protection.* The proteolytic enzymes not only break down inflammatory proteins including kinins and fibrin but also enhance the breakdown and removal of damaged tissue improving lymphatic drainage.

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infl7

NorLox by Neuroscience 60 Vcaps NorLox by Neuroscience 60 Vcaps -
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NorLOX supports healthy brain function by inhibiting inflammation which triggers both the sympathetic and hypothalamic-pituitary-adrenal stress response. Changes in mood and mental health have been associated with inflammation. NorLOX contains acetyl-11-keto-beta-boswellic acid which is a potent inhibitor of 5-lipoxygenase (5-LOX), the enzyme responsible for the production of pro-inflammatory leukotrienes. Acetyl-11-keto-beta-boswellic acid also prevents TNF-α induced expression of matrix metalloproteinases (MMPs) and upregulation of adhesion molecules, both of which are involved in the movement of leukocytes to the site of inflammation. NorLOX also provides 5-HTP to support serotonin levels which can be reduced by pro-inflammatory cytokines. Acetyl-L-carnitine is included as a cognitive enhancer which acts by promoting mitochondrial health and modulating redox-dependent mechanisms which support neuron survival and longevity.

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nsnor $45.00

Nrf2 Pathway Activator Nrf2 Pathway Activator -
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Nrf2 Pathway Activator is an exclusive formula designed to activate the Nrf2 genetic pathway that regulates the production of important antioxidants such as glutathione and superoxide dismutase (SOD), as well as detoxification enzymes including glutathione- S transferase, while down-regulating inflammatory factors such as NF-kB. Each of the ingredients in this product is backed by extensive research in peer-reviewed journals.Activation of the Nrf2 pathway may also be important in treatment of multiple sclerosis,and other neurodegenerative diseases such as Alzheimer or Parkinson disease. * Antioxidant Support * Anti-Inflammatory Support * Detoxification Enhancement

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xymnrf2 $44.90

Similase by Tyler Encapsulations 90 Veg Capsules Similase by Tyler Encapsulations 90 Veg Capsules -
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Similase by Tyler is a comprehensive, high-potency Plant Enzyme supplement that supports digestion of all food groups. Unlike animal-derived pancreatic enzymes, Plant Enzymes in Similase are acid-stable and active from pH 2 to 12.

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simil $21.99

Stimulated Cytokine Analysis by NeuroScience Stimulated Cytokine Analysis by NeuroScience -
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This profile provides an assessment of cytokines secreted by Th1, Th2, Th17, and Treg T cell subsets. Th1 cytokines are associated with bacterial infection and certain autoimmune disorders, while Th2 cytokines indicate allergic responses or mucosal parasitic infections. Th17 cells are implicated in autoimmune disorders; but IL-17 is also key to maintaining a protective intestinal mucosal barrier and to fighting bacterial, mycobacterial, and fungal infections. Requires a blood draw. You receive the results. Blood draw fee not included in price. Not Available in New York.

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ns5105 $435.00

Telephone Consultation Telephone Consultation -
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Valerie Balandra ARNP is available for telephone consultations. Discuss your health condition, supplement or medication regimen, which tests to order, or review testing done in the past. She will use her 20 years of natural and mental health experience to get you on the track to good health. Choose 15 minute or 30 minute consultation times.

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