Your intestinal wall constitutes a first-line defense against many potentially harmful substances (food, environmental toxins, bacteria, and other microbes). This barrier is very efficient and effective under normal conditions.
On the other hand, stress, diet, sleep deprivation, infection, and myriad diseases compromise this intestinal barrier function. When this happens, substances that are normally unable to cross the cells lining your intestine (epithelial cells) now find their way into your general circulation.
Because 80% of your immune cells reside just underneath the cells lining your intestinal tract, these invaders launch an exaggerated immune reaction. This immune reaction in turn increases intestinal permeability further, and a vicious cycle ensues.
Many studies support a model where cycles of increased intestinal permeability, intestinal immune activation, and subsequent immune-mediated barrier loss contribute to disease progression in many intestinal and systemic conditions.
This association between increased intestinal permeability and disease has caught the attention of the public, leading to a rise in popularity of the diagnosis “leaky gut syndrome,” which encompasses a range of systemic disorders. As proponents of this model, we at IP (Integrative Psychiatry (or should we change our name to Intestinal Permeability?)) believe that barrier restoration will improve/cure the underlying pathology that drives many modern diseases of civilization.
That is why our first step in treating so many seemingly diverse conditions is to “Seal and Heal” your gut.

With that as background, we are proud to announce the arrival of a new product – Leaky Gut Repair Powder – that combines those compounds and ingredients that have the most robust scientific data supporting their beneficial effects on restoring the integrity of your intestinal lining.
Intestinal permeability defects: is it time to treat? Odenwald MA, Turner JR. Clin Gastroenterol Hepatol. 2013 Sep;11(9):1075-83.
Possible links between intestinal permeability and food processing: A potential therapeutic niche for glutamine. Rapin JR, Wiernsperger N. Clinics (Sao Paulo). 2010 Jun;65(6):635-43.
Leaky Gut Repair Powder helps to seal and heal intestinal permeability issues or “leaky gut”. This unique formula provides powerful leaky gut treatment and contains concentrated extract of licorice that has been processed to remove glycyrrhizin—thus reducing risk of side effects associated with licorice. Glutamine is the primary fuel and nitrogen source for the mucosal lining of the gastrointestinal (GI) tract. Arabinogalactan from the North American larch tree is a naturally occurring polysaccharide that provides excellent support for GI health. Research suggests that arabinogalactan plays a role in the promotion of gut microflora and may increase beneficial short-chain fatty acid production, it also provides a protective role against dietary lectins. Aloe vera leaf extract helps heal the gut and has been processed to remove the bitter principles and prevent a laxative effect.