Pyroluria: How Pyrroles Affect Physical and Mental Health
Pyroluria is a genetically acquired chemical imbalance in which the body produces an abnormally large number of pyrroles. A pyrolle is a chemical consisting of a 5 membered aromatic ring. These chemicals are the byproduct of hemoglobin synthesis and have no known function in the body; they are normally excreted in the urine. Most people have very few pyrroles in their system at any given time; certain individuals, however, have an unusually high number of pyrroles in their bodies, resulting in a condition known as pyroluria.
Symptoms of Pyroluria
Individuals with pyroluria exhibit a wide range of physical, emotional and cognitive symptoms; some common characteristics of pyrolurics are described here:
Testing and Diagnosis
With such a wide range of symptoms, pyroluria is frequently misdiagnosed, and therefore often treated inappropriately. While patients exhibiting certain symptoms such as depression and anxiety often experience some degree of relief from antidepressant medications, these effects are temporary and do not resolve the underlying problem.
Treatment of Pyroluria
Pyrolurics generally respond very well to nutritional treatments which emphasize zinc and B6 supplementation. Many patients experience some degree of relief within several days of treatment, and most undergo substantial recovery within 3 to 6 months. However, it is important to remember that treating this disease is an ongoing, lifelong process; those who discontinue treatment typically experience a near-immediate return of their symptoms.
The symptoms of pyroluria are frequently mistaken for signs of other illnesses; all too often, doctors prescribe medications to treat the overt symptoms without taking the time to further investigate their root cause. With the appropriate lab testing, your health care provider can determine the core problem. Once a pyrrole disorder has been identified, you will be able to take the measures necessary to correct the problem, improving your health and your overall quality of life.
Kryptopyrrole Pyroluria Urine Test
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