Pure Encapsulations Nitric Oxide Ultra Capsules 120c offers a blend of CranLoad™ and citrulline to support healthy blood flow by targeting nitric oxide production and flow-mediated dilation. The formula centers around CranLoad™, a novel fruit blend developed as part of an extensive research program with the Institute of Nutrition and Functional Foods (INAF) and Université Laval in Quebec, Canada. CranLoad™ delivers a unique cranberry and grape seed blend that has been the subject of several trials. Cranberries and grapes are particularly generous sources of proanthocyanidins and other polyphenols. In addition to being powerful antioxidants, these compounds offer specific vascular support mechanisms that are associated with enhanced endothelial function. Research indicates that CranLoad™ provides statistically significant support for healthy flow-mediated dilation (FMD), an effect similar to arginine administration. FMD reflects blood vessel dilation mediated by nitric oxide synthase (NOS), an enzyme that generates the endogenous vasodilator, nitric oxide. In one study, the peak increase in brachial artery diameter following CranLoad™ supplementation was 2.8% at 60 minutes. A similar physiological effect has been demonstrated with arginine. Citrulline is included to support nitric oxide production in the blood vessel endothelium and other tissues. Research indicates that citrulline increases plasma arginine in a dose dependent manner and to a greater degree than arginine supplementation.
Nitric Oxide Ultra (capsules) offers a unique clinically researched blend of cranberry and grape seed extracts combined with citrulline to support blood flow and vascular health, including nitric oxide production, flow-mediation dilation, and endothelial function.
four vegetarian capsules contain:
l-citrulline (free-form) 2,000 mg
CranLoad™ proprietary blend 765 mg
providing cranberry (vaccinium macrocarpon) extract (fruit) and grape (vitis vinifera) extract (seed)
ascorbyl palmitate (fat-soluble vitamin C) 40 mg
other ingredients: vegetarian capsule (cellulose, water)
2-4 capsules daily, in divided doses, between meals.
About the Manufacturer
At Pure Encapsulations, ingredient quality and manufacturing excellence are their most important priorities. They manufacture their supplements in their own state-of-the-art facility in Sudbury, Massachusetts. Every step of the manufacturing process exceeds the requirements for nutritional supplement manufacturing. Each piece of equipment used in the manufacture of Pure Encapsulations supplements is dismantled and sterilized before each production run. Pure Encapsulations was founded by practicing physicians who were seeking the highest quality hypo-allergenic supplements for their patients.