Urinary neuro-biogenic amines provide an overall assessment of a patient's ability to synthesize and metabolize neurotransmitters, both in the periphery and, for some enzymes, behind the blood brain barrier as well. Alterations in urinary neurotransmitter status may be associated with a variety of conditions including metabolic disorders, mood/behavioral disorders, and in rare occasions the presence of certain tumors. Associations between urinary neurotransmitter levels and health conditions have been documented in scientific literature and may provide valuable insights as part of a comprehensive health assessment.
Neurotransmitters, or "biogenic amines" are secreted from pre-synaptic neurons into the synapse between nerve cells to stimulate receptors on post-synaptic neurons. The neurotransmitters are all produced from essential aromatic amino acids. Neurotransmitter metabolism may be mediated by a variety of enzymes expressed differently throughout the body. Circulating levels of neurotransmitters and metabolites may have distinctive sources. Urinary levels of neuro-biogenic amines primarily reflect the activity of the peripheral and GIT enteric nervous systems. Up to 20% of urinary neurotransmitters are estimated to originate in the CNS.
A lack of nutritional cofactors (vitamins, minerals) required for normal enzyme function may decrease enzyme function and neurotransmitter levels. Neurotransmitter receptors and metabolic enzymes may be subject to mutations and single nucleotide polymorphisms (SNPs) that may affect receptor or enzyme function. Normal neurotransmitter receptor function is also necessary for normal neurotransmitter activity. Neurotransmitter levels may be influenced by diet, lifestyle and other health conditions such as: high sodium intake, age, gender, body mass index, kidney function, environmental exposures, infection and tobacco use.
Urinary neuro-biogenic amines provide an overall assessment of a patient's ability to synthesize and metabolize neurotransmitters, which must occur in both the peripheral nervous system and behind the blood brain barrier (BBB). Alterations in urinary neurotransmitter status may result from a variety of conditions including metabolic disorders, mood/behavioral disorders, environmental exposures or (rarely) the presence of certain tumors. Evaluation of neurotransmitters may provide increased clarity about a patient's health and functional status.
Urinary neuro-biogenic amines are a non-invasive way to assess the synthesis and metabolism of neurotransmitter molecules essential for normal function. Information gained through neurotransmitter testing may provide therapeutic opportunities that improve clinical success and patient health outcomes. Associations between urinary neurotransmitter levels and health conditions have been documented in scientific literature and may provide valuable insight as part of a comprehensive health assessment.
- Purchase on our secure website.
- Lab order is provided by us.
- You receive a collection kit for urine to collect urine at home and mail to the lab.
- You receive the results by email within 2-3 weeks.
Sample Report Comp Neuro.pdf
About the Manufacturer
Doctors Data is a specialist and pioneer in essential and toxic elemental testing of multiple human tissues, the laboratory offers a wide array of functional testing. Doctors Data's tests are utilized in the assessment, detection, prevention, and treatment of heavy metal burden, nutritional deficiencies, gastrointestinal function, hepatic detoxification, metabolic abnormalities, and diseases of environmental origin.