Description
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Organic acids are metabolic intermediates produced in pathways of central energy production, detoxification, neurotransmitter breakdown, or intestinal microbial activity. Accumulation of specific organic acids in urine often signals a metabolic inhibition or block. This may be due to a nutrient deficiency, an inherited enzyme deficit, toxic build-up, or drug effect.
From a single urine specimen, the Organix Profile provides important information in the areas of:
- Vitamin and mineral insufficiencies
- Amino acid insufficiencies like carnitine and NAC
- Oxidative damage and anti-oxidant sufficiency markers
- Indicators to assess detoxification sufficiency
- The best functional markers of B-complex deficiency
- Neurotransmitter metabolites to assess CNS function
- Mitochondrial energy production assessment via citric acid cycle components
- Methylation sufficiency status
- Lipoic acid and CoQ10 sufficiency markers
- Specific dysbiosis markers for bacterial and yeast overgrowth
Analytes
FATTY ACID METABOLISM
Adipate
Suberate
Ethylmalonate
CARBOHYDRATE METABOLISM
Pyruvate
L-Lactate*
Beta-Hydroxybutyrate
ENERGY PRODUCTION (CITRIC ACID CYCLE)
Citrate
cis-Aconitate
Isocitrate
Alpha-Ketoglutarate
Succinate
Fumarate
Malate
Hydroxymethylglutarate
B-COMPLEX VITAMIN MARKERS
Alpha-Ketoisovalerate
Alpha-Ketoisocaproate
Alpha-Keto-Beta-Methylvalerate
Xanthurenate
Beta-Hydroxyisovalerate
METHYLATION COFACTOR MARKERS
Methylmalonate (methylmalonic acid)
Formiminoglutamate
NEUROTRANSMITTER METABOLISM MARKERS
Vanilmandelate
Homvanillate
5-hydroxyindoleacetate
Kynurenate
Quinolinate
Picolinate*
OXIDATIVE DAMAGE AND ANTIOXIDANT MARKERS
p-Hydroxyphenyllactate
8-Hydroxy-2′-deoxyguanosine*
DETOXIFICATON INDICATORS
2-Methylhippurate
Orotate
Glucarate
Alpha-Hydroxybutyrate
Pyroglutamate
Sulfate
BACTERIAL-GENERAL
Benzoate
Hippurate
Phenylacetate
Phenylpropionate
p-Hydroxybenzoate
p-Hydroxyphenylacetate
Indican
Tricarballylate
L.ACIDOPHILUS/GENERAL BACTERIA
D-Lactate*
CLOSTRIDIAL SPECIES
3,4 Dihydroxyphenylpropionate
YEAST/FUNGAL
D-Arabinitol*
Creatinine