Karuna SAM-e Plus 30t contains the tosylate form of SAM-e as used extensively in clinical trials, and includes several other ingredients found in studies to support and facilitate these functions. SAM-e Plus tablets are enterically-coated, essential for preventing demethylation in the stomach. Over a decade of rigorous clinical studies in Europe and elsewhere have established SAM-e (S-adenosyl-L-methionine, an essential methylation and transulfuration cofactor) as a useful tool for supporting normal mood regulation, and joint and liver health. SAM-e increases cell membrane fluidity, up-regulates neurotransmitter receptor number, and enhances neurotransmitter receptor affinity. SAM-e supports healthy joints both by increasing the number of articular chondrocytes, and by stimulating the synthesis of protective sulfated proteoglycans therein. SAM-e also protects synovial cells against pro-inflammatory prostanoids, and blocks enzymes that degrade cartilage. SAM-e is a precursor of the critical antioxidant glutathione, a key molecule in the detoxification process in the liver.
Suggested use for adults: Two to four tablets daily, or as directed by your health care practitioner. This product contains no yeast, wheat, soy, corn, milk, salt, sugar, artificial coloring, preservatives or falvoring. This product is intended for professional use and is manufactured under strict quality control to ensure the optimum in purity, potency and reliability.
Serving Size 2 Tablets*
Servings per Container 15
Amount per serving
B3 (niacinamide) 30 mg
B6 (pyridoxine HCI) 2 mg
Folic Acid 400 mcg
B12 (cyanocobalamin) 20 mcg
SAM-e (tosylate disulfate) 400 mg
Choline (bitartrate) 50 mg
Other ingredients: calcium sulfate, stearic acid, silica, vegetable coating
*Enterically coated tablets
Keep in a cool, dry place, tightly capped.
Calcium , Cellulose, Stearic acid
About the Manufacturer
Karuna creates the best products possible, utilizing research-validated ingredients of verified freshness, purity and potency.