Anti-InflammaLox contains ingredients backed by years of use in traditional herbal medicine, as well as by published research in peer-reviewed journals. Boswellia serrata, white willow bark and bioflavonoids have all been shown to possess good anti-inflammatory and analgesic properties through the inhibition of COX-2 and 5-LOX enzymes. The proprietary bioflavonoid blend provides antioxidant protection against damage to soft tissue.
- Antioxidant Support
Dosing: Effectiveness appears to be dependent upon dose and length of treatment with relief of discomfort at a higher dose and over a period of time.
Two capsules, two or more times a day have been reported to be effective.
Salicin (White Willow Bark, Salix alba) contains salicylates, tannins and flavonoids. Decoctions of the bark have been used to treat pain, fever and headaches for approximately 2000 years. The role of salicylates in inflammation and pain management is well-documented in medicine as white willow bark was the forerunner of aspirin. In studies willow bark extract strongly prevented PGE2 and cytokine release. A 2007 systemic review of the literature found moderate evidence for short-term improvements in pain with daily doses standardized to 120 mg or 240 mg salicin.
5•Loxin®, a standardized Boswellia serrata extract enriched to 30% 3-acetyl-11-keto-b-boswellic acid (AKBA), is ten times more concentrated than ordinary boswellia. Boswellia is an ayurvedic herb whose principle constituents boswellic acid and alpha-boswellic acid may maintain healthy leukotriene metabolism by reducing the activity of the enzyme 5-lipoxygenase. Matrix metalloproteinase (MMP), a class of enzymes that selectively hydrolyze peptide bonds and degrade structural proteins, play a crucial role in the degradation of joint tissues. 5•Loxin® shows significant inhibition against several MMP’s. It prevents formation of human recombinant TNFa inducible MMPs, responsible for cartilage degradation and inflammatory mediators of apoptosis and adhesion molecules including VCAM-1 and ICAM-1. Various randomized, double-blind, placebo-controlled, crossover studies have demonstrated the efficacy of boswellia.[6,7,8]
Metabolism of Salicin: An oral dose of salicin is rapidly and completely metabolized to mostly salicylic acid. After biotransformation to salicin in the GI tract, B-glucuronidase activity and hydrolysis covert salicin to saligenin. Saligenin is further converted to salicylic acid in the liver by the cytochrome P- 450 system. After an oral dose (240mg) was given to healthy volunteers, the Tmax was less than two hours and Cmax was 1.2 mg/L, respectively. Salicylic acid is eliminated in urine as salicyluric acid.
BerryVin™, a bioflavonoid-rich, high ORAC berry powder containing blueberries, blackberries, strawberries, and cranberries, along with grape and pomegranate extracts provides strong antioxidant support of soft tissues. The bioflavonoids may act synergistically to inhibit cycloxygenase, lipoxygenase and phospholipase.
• Antioxidant Support
Each of the ingredients in this exclusive formula is backed by years of use in traditional herbal medicine, as well as by published research in peer-reviewed journals. Boswellia serrata, white willow bark and bioflavonoids have all been shown to possess good anti-inflammatory and analgesic properties through the inhibition of COX-2 and 5-LOX enzymes. The proprietary bioflavonoid blend provides antioxidant protection against damage to soft tissue.
About the Manufacturer
The IP Formula line provides quality brain nutrition at affordable prices. Our line of brain vitamins, amino acid supplements, and omega 3 fatty acids help to increase brain function and stabilize mood and weight issues by supplying the brain food that is not being supplied or absorbed from your diet.
All of our brain nutrition products are manufactured in a state of the art and NNFA GMP Certified production facility. Our goal is to provide the highest quality nutritional supplements at prices that are affordable.
We guarantee that our products meet label potency, are void of all toxic metals or microbial contaminants, and are made in a hygienic environment, our herbals are authentic and active, and a standard operating procedure (SOP) is in use for all aspects of production.