Description:
Metametrix Organix Urine Organic Acid Test provides a view into the body's cellular metabolic processes and the efficiency of metabolic function. Identifying metabolic blocks that can be treated nutritionally allows individual tailoring of interventions that maximize patient responses and lead to improved patient outcomes. Doctors Order Provided, you receive the results. Organic acids are metabolic intermediates produced in pathways of central energy production, detoxification, neurotransmitter breakdown, or intestinal microbial activity. Accumulation of specific organic acids in urine often signals a metabolic inhibition or block. This may be due to a nutrient deficiency, an inherited enzyme deficit, toxic build-up, or drug effect.

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Identifying the cause of chronic illness using the Organix Comprehensive Profile is the first step toward achieving a favorable outcome. Integrative clinicians rely on the Organix™ Profile to reveal the nutritional and metabolic basis of patient symptoms, just as traditional practitioners might use a serum chemistry to establish a diagnostic baseline. The Organix Profile provides a view into the body's cellular metabolic processes and the efficiency of metabolic function. Identifying metabolic blocks that can be treated nutritionally allows individual tailoring of interventions that maximize patient responses and lead to improved patient outcomes.

From a single urine specimen, the Organix Profile provides important information in the areas of:

• Vitamin and mineral insufficiencies
• Amino acid insufficiencies like carnitine and NAC
• Oxidative damage and anti-oxidant sufficiency markers
• Indicators to assess detoxification sufficiency
• The best functional markers of B-complex deficiency
• Neurotransmitter metabolites to assess CNS function
• Mitochondrial energy production assessment via citric acid cycle components
• Methylation sufficiency status
• Lipoic acid and CoQ10 sufficiency markers
• Specific dysbiosis markers for bacterial and yeast overgrowth

Analytes

FATTY ACID METABOLISM
Adipate
Suberate
Ethylmalonate

CARBOHYDRATE METABOLISM
Pyruvate
L-Lactate*
Beta-Hydroxybutyrate

ENERGY PRODUCTION (CITRIC ACID CYCLE)
Citrate
cis-Aconitate
Isocitrate
Alpha-Ketoglutarate
Succinate
Fumarate
Malate
Hydroxymethylglutarate

B-COMPLEX VITAMIN MARKERS
Alpha-Ketoisovalerate
Alpha-Ketoisocaproate
Alpha-Keto-Beta-Methylvalerate
Xanthurenate
Beta-Hydroxyisovalerate

METHYLATION COFACTOR MARKERS
Methylmalonate
Formiminoglutamate

NEUROTRANSMITTER METABOLISM MARKERS
Vanilmandelate
Homvanillate
5-hydroxyindoleacetate
Kynurenate
Quinolinate
Picolinate*

OXIDATIVE DAMAGE AND ANTIOXIDANT MARKERS

p-Hydroxyphenyllactate
8-Hydroxy-2'-deoxyguanosine*

DETOXIFICATON INDICATORS
2-Methylhippurate
Orotate
Glucarate
Alpha-Hydroxybutyrate
Pyroglutamate
Sulfate

BACTERIAL-GENERAL
Benzoate
Hippurate
Phenylacetate
Phenylpropionate
p-Hydroxybenzoate
p-Hydroxyphenylacetate
Indican
Tricarballylate

L.ACIDOPHILUS/GENERAL BACTERIA
D-Lactate*

CLOSTRIDIAL SPECIES
3,4 Dihydroxyphenylpropionate

YEAST/FUNGAL
D-Arabinitol*

Creatinine