Description:
Genova Diagnostics NeuroGenomic Profile evaluates single nucleotide polymorphisms (SNPs) in genes that modulate methylation, glutathione conjugation, oxidative protection and the potential to evaluate vascular oxidation. Requires a blood draw. Small fee required to draw blood at lab of your choice. No doctors order required. You receive the results. NOT AVAILABLE IN NEW YORK.

The test uncovers potential genetic susceptibility to:

• ·Neurodegenerative Disorders

• Developmental Issues
• Mood Disorders
• Oxidative Stress
• Detoxification Capacity
• Methylation
• MTHFR (methylenetetrahydrofolate reductase)
• COMT (catechol-O-methyltransferase)

These genes affect how homocysteine and methionine are metabolized to support formation
of S-adenosylmethionine (SAMe). The ability to donate methyl groups affects neurologic
function and is modifiable by proper B-vitamin intake.
Detoxification
· GSTM (glutathione-s-transferase, M, isoforum)

· GSTP (glutathione-s-transferase, P, isoforum)

These genes are responsible for detoxifying products of oxidative stress and carcinogens.
Variants decrease detoxification capacity.
Oxidative Protection
· SOD-2 (Superoxide dismutase -2)

These genetic variants alter anti-oxidant enzyme activity and modify requirements for antioxidants.

ANALYTE LIST: