Description:
Genova Diagnostics Intestinal Permeability Assessment analyzes urine for the clearance of two non-metabolized sugars, lactulose and mannitol. Identifies "leaky gut", and malabsorption.The Intestinal Permeability Assessment directly measures the ability of two nonmetabolized sugar molecules –mannitol and lactulose–to permeate the intestinal mucosa. Simple sample you collect at home and send to the lab. Doctor's orders provided. You receive the results. NOT AVAILABLE TO NEW YORK RESIDENTS.

Mannitol is easily absorbed and serves as a marker of transcellular uptake, while lactulose is only slightly absorbed and serves as a marker for mucosal integrity. To perform the test, the patient mixes premeasured amounts of lactulose and mannitol and drinks the challenge substance. The test measures the amount of lactulose and mannitol recovered in a urine sample over the next 6 hours.Urine specimen you collect at home and mail to the lab. You receive a copy of the results.