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EstroEssence Metabolism Plus is ideal for: • The prevention and treatment of hormone-related symptoms and conditions • Prescribing and monitoring Hormone Replacement Therapy (HRT) • Assessing the risk of hormone-related disease, including breast cancer
EstroEssence Metabolism Plus evaluates:
• Estrogens and metabolites • Progesterone metabolites • Androgens and metabolites • Human Growth Hormone • Anabolic/Catabolic Balance • Methylation capacity • Thyroid hormone • Aldosterone • Adrenal hormones and metabolites
The Benefits of Urine Hormone Testing:
First-Morning-Void OR 24-hour urine collection These simple, at-home collection options offer the advantage of a time average, effectively integrating spikes that may occur in these hormones over time. Measures the free, bio-available fraction of hormones Urinary testing measures the portion of hormones that are active in the body. Measures the metabolites of these important steroid hormones These metabolites contribute to provide a robust analysis of hormonal excess or deficiency, and help to assess the adequacy and safety of hormone replacement therapy (HRT). Anabolic/Catabolic Balance (ACB) The ACB evaluates the ability for “growth and healing” (anabolic) versus the state of “wear and tear” (catabolic). Methylation Capacity Methylation is required for effectively eliminating carcinogenic hormone metabolites, and for activating protective hormones against cancer.
Treatment Therapy is directed at the source of the abnormality, which may include: • HRT – estrogen, progesterone, androgens, thyroid, cortisol, etc. • Methylation support - S-adenosyl-methionine (SAMe), B vitamins • Estrogen Metabolism support - Indole-3-carbinol (I3C) and/or Diindolemethane (DIM)
Further treatments may be indicated by specific genomic testing (EstroGenomics™), which identifies modifiable genetic influences that can impair healthy hormone metabolism.
•Analytes tested: Estradiol Estriol Estrone 2-Hydroxyestrone 4-Hydroxyestrone 16-α-hydroxestrone 2 Methoxyestrone 4 Methoxyestrone 2:16 Ratio 2 Methoxyestrone: 2 Hydroxyestrone Ratio 4 Methoxyestrone: 4 Hydroxyestrone Ratio Pregnanetriol Tetrahydrocortisol (THF) Tetrahydrocortisone (THE) Tetrahydrodeoxycortisol (THS) 17-Hydroxy-corticosteroids DHEA Androsterone Etiocholanolone 11-Hydroxy-androsterone 11-Hydroxy-etiocholanolone 11-Keto-androsterone 11-Keto-etiocholanolone 17-Ketosteroids Anabolic/Catabolic Balance E/A: 5-β/5-αRatio THF/a-THF Ratio 11-β-HSD Index Triiodothyronine, T3 Human Growth Hormone (hGH) Aldosterone (available on 24-hour only) • Specimen Requirements: 120ml urine
• Before Taking this Test: Premenopausal women, note date of menstrual cycle on the requisition.
Recommend women on HRT or hormonal contraceptives, to obtain specimen approximately 8-10 hours AFTER the last dose. |