Description:
Essential Estrogens provides a focused overview of estrogen balance in both pre- and post-menopausal women, using a single urine sample to evaluate dynamics of sex steroid metabolism that can profoundly affect a woman's health throughout her lifetime.Designed to assist in the prevention and treatment of estrogen-related symptoms and conditions. Simple urine collection you do at home and mail to the lab. You receive the results and recommendations. NOT AVAILABLE TO NEW YORK RESIDENTS.

This profile measures the following urinary estrogens and estrogen metabolites, and includes an assessment of estrogen methylation, which is a critical step in the protective mechanism of estrogen metabolism.

ANALYTE LIST: 

Interpretation
Estrogens, particularly estrone and estradiol, are well described in the literature regarding the health and disease of estrogen sensitive tissues.

Estrogen deficiency
• Osteoporosis
• Amenorrhea
• Menopausal symptoms

Estrogen excess
• Menorrhagia
• Uterine fibroids
• Anxiety/irritability
• Breast Cancer

Estrogen metabolites are proven to convey protection (if balanced) or increased risk (if imbalanced) for disease.

Estrogen metabolite imbalance results in increased risk of:
• Breast cancer
• Osteoporosis
• Prostate cancer

Estrogen methylation is a critical step in the protective mechanism of estrogen metabolism. Methylation is required for the protective effects of 2-hydroxy-estrone, and for the safe detoxification of 4-hydroxy-estrone.

Treatment
Therapy is directed at the source of the abnormality, which may include treatments such as ERT in estrogen deficiency, S-adenosyl-methionine (SAMe) to improve estrogen methylation, and Indole-3-carbinol (I3C) and/or Di-indolemethane (DIM) for balancing estrogen metabolites.