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Cyrex Array 3 – Wheat Gluten Autoimmunity Reactivity Profile

Cyrex Array 3 – Wheat Gluten Autoimmunity Reactivity Profile is the most sensitive test available for gluten reactivity. Measuring immune response to an array of wheat antigens increases the sensitivity andspecificity, and will provide greater confidence in formulation of a diagnosis that allows for better patient compliance with a gluten-free diet.
  • Purchase on our secure website.
  • Lab order is provided by us.
  • You receive a collection kit for a blood draw. This tests requires a blood draw at a local lab.
  • You receive the results by email within 2-3 weeks.
Assessing wheat/gluten reactivity and intestinal autoimmunity is recommended for patients who:
Helpful for those who:
  • Have gut dysbiosis, which appears to be resistant to standard therapy
  • Are suspected of having intestinal mucosal damage
  • Complain of food allergy and intolerance
  • Complain of chemical hypersensitivity
  • Present multiple-symptom complaints (including Chronic Fatigue Syndrome and Fibromyalgia)
  • Suffer from abnormal immune cell count and function
  • May suffer from blood-brain barrier permeability, depression, or neuroautoimmunity

Also helpful for those with Neuroautoimmune issues to consider:

Thyroiditis
Arthritis
Myocarditis
Dermatitis
Endocrinopathy
Polyendocrinopathy
Osteoarthritis
Pernicious Anemia
Other

$399.00

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Description

Wheat/Gluten Proteome Reactivity & Autoimmunity

Wheat IgG
Wheat IgA
Wheat Germ Agglutinin IgG
Wheat Germ Agglutinin IgA
Native + Deamidated Alpha-Gliadin-33-mer IgG
Native + Deamidated Alpha-Gliadin-33-mer IgA
Alpha-Gliadin-17-mer IgG
Alpha-Gliadin-17-mer IgA
Gamma-Gliadin-15-mer IgG
Gamma-Gliadin-15-mer IgA
Omega-Gliadin-17-mer IgG
Omega-Gliadin-17-mer IgA
Glutenin-21-mer IgG
Glutenin-21-mer IgA
Gluteomorphin+Prodynorphin IgG
Gluteomorphin+Prodynorphin IgA
Gliadin-Transglutaminase IgG
Gliadin-Transglutaminase IgA
Transglutaminase-2 IgG
Transglutaminase-2 IgA
Transglutaminase-3 IgG
Transglutaminase-3 IgA
Transglutaminase-6 IgG
Transglutaminase-6 IgA

Specimen Requirement:

Collect: 5 mL red top or tiger top
Transport: 2 mL serum
Pediatric: Transport 0.5 mL serum

Brand

Cyrex Labs

Cyrex Labs is an advanced clinical laboratory focusing on mucosal, cellular and humoral immunology and specializing in antibody arrays for complex thyroid, gluten and other food-associated autoimmunities and related neurodysregulation. Cyrex’s Scientific Advisory Board, comprised of experts from a variety of medical and research disciplines, brings together the latest findings from medical research and the assessment needs of today’s healthcare professionals. Out of this collaboration, Cyrex develops the next generation of clinical lab testing that is required to care for present-day complex maladies.

Cyrex adheres to and surpasses the highest standards of clinical laboratory testing worldwide. A Cyrex-designed quality control criterion called The Double Assurance System (QC2™) is the standard operating procedure at Cyrex Laboratories. In fact, Cyrex’s proprietary QC2™ method enhances the reproducibility, specificity and sensitivity of all Cyrex arrays. Only Cyrex tests contain the accuracy enhancements provided by The Double Assurance System.

Before ordering please consider the following: • Patient has been clear of immunosuppressant AND/OR corticosteroid drugs for at least 60 days. • Patient has had timely and adequate antigen exposure in order to measure antibody responses.

Q: Are there any medications, foods, conditions or other factors that could interfere with the results of a Cyrex test?

A: Yes. While Cyrex is unable to provide an exhaustive answer to this question due to the interactive complexities and varieties of medications and patient circumstances, the following has been noted:

a. Immunosuppressant and corticosteroid drugs can reduce antibody production and cause false negative results. b. Limited assessments on the effects of aspirin, acetaminophen, and antipsychotics on Arrays 1-4 have been performed. No noticeable effects were observed. c. Inhalers can affect the results of Cyrex's oral fluid testing (Array 1). Wait two weeks after completion of inhalant dosages before collecting the specimen. d. Unknown cross-reactive epitopes from foods and microorganisms may stimulate the antibody production in the absence of a true antigen. Cyrex has already developed Array 4 in order to recognize the most common antigens in this regard. e. A gluten-free diet can cause false negative results on gluten protein/peptide tests. f. Certain conditions, such as ileal pouch surgery, may cause a false positive celiac serology.1

1. Lian L, Remzi FH, Kiran RP, Fazio VW, Shen B. Clinical implication of false-positive celiac serology in patients with ileal pouch. Dis Colon Rectum. 2010 Oct; 53(10):1446-1451.
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